学术堂首页 | 文献求助论文范文 | 论文题目 | 参考文献 | 开题报告 | 论文格式 | 摘要提纲 | 论文致谢 | 论文查重 | 论文答辩 | 论文发表 | 期刊杂志 | 论文写作 | 论文PPT
学术堂专业论文学习平台您当前的位置:学术堂 > 毕业论文 > 在职硕士论文 > 同等学力硕士论文 > 临床医学硕士论文

热射病致中枢神经系统病变诊疗结论与参考文献

来源:学术堂 作者:韩老师
发布于:2015-05-12 共3971字
    本篇论文目录导航:

【第1部分】中暑热射病致CNS病变的病例分析
【第2部分】热射病致CNS病变9例临床资料与诊断方法
【第3部分】热射病致多系统损害治疗结果与讨论
【第4部分】 热射病致中枢神经系统病变诊疗结论与参考文献
【第5部分】热射病发病机制的研究进展文献综述

  结论
  
  1.热射病导致中枢神经系统损伤,具有致残率高、死亡率高的特点,临床神经功能缺损症状重,但颇脑影像学表现较轻。

  2.高热所致中枢神经系统损害呈多部位、多类型的特点,热射病中脑细胞血管源性水肿所致中暑神经损伤干预及时可痊愈,而细胞毒性水肿易导致神经元细胞永久性损伤,遗留神经缺损后遗症。

  3.热射病的急性期炎症反应具有局限性,于“最佳干预时间”窗内给予及时充分的治疗,预后较好。

  4.伴有基础病史特别是神经系统疾病的热射病患者,病情进展迅速,病情重,预后差。

  5.热射病所引发的SIRS致各系统损害在治疗进程中不会因核心体温的正常化及症状改善而终止,建议热射病患者持续住院治疗时间至少应>14天,此期间早期抗炎治疗及炎症介质的清除可有效改善病情,预防迟发性的神经损伤。  
  
  参考文献
  
  [1]Bouchama A. Heatstroke: a new look at an ancient disease.Intensive Care Med,1995; 21623-5.
  [2]Grogan H,Hopkins PM.Heat stroke: implications for critical care and anesthesia[J]. BrJAnaesth,2002,88(5) :700-707.
  [3]唐吉刚,王树才,曹霞,等。劳力性热射病致横纹肌溶解症八例[J].中华神经科杂志。2014, 46(7); 454-457.
  [4]Dematte JE,O'Mara K,Buescher J,et al. Near-fatal heat stroke during the 1995 heat wave in Chicago [J]. Ann Intern Med,1998,129:173-81.
  [5]Bouchama A, Knochel JR Heat stroke [J], N Engl J Med, 2002,346(25); 1978-1988.
  [6]Guerrero WR,Varghese S,Savitz S, et al. Heat stress presenting with encephalopathy and MRI findings of diffuse cerebral and Hemorrhage [J], BMC Neurology 2013,13(63):doi:10.1186/1471-2377-13-63.
  [7]Chaa SY,Kanga TH, Kimb SJ,etal ? Selective anterograde amnesia associated with hippocampal and splenial damage after heat stroke[J].Clinical neurology and neurosurgery,2013,115(9):1867-1870.
  [8]吴小坤,李佳,赵娟,等。1例热射病的MRI影像表现[J].中风神经疾病杂志,2013,30(04):0378-0379.
  [9]Mahajan S,Schucany WG Symmetric bilateral caudate, hippocampal, cerebellar,and subcortical white matter MRI abnormalities in an adult patient with heat stroke. Proc(Bayl Univ MedCent),2008 21(4): 433-436,.
  [10]Atsuhito Fuse, Kazuo Yamashir, Yutaka Oji,etal.Reversible Focal Cerebral Cortical Lesions in a Patient with Heat Stroke [J]. Intern Med, 2013,52: 377-380.
  [11]Carmine Franco Muccioa, Elvio De Blasiob, Maria Vendittob, et al.Heat-stroke in an epileptic patient treated by topiramate:Follow-up by magnetic resonance imaging including diffusion-weighted imaging with apparent diffusion coefficient measure[J].Clinical Neurology andNeurosurge, 2013, 115: 1558-1560.
  [12]McLaughlin CT,Kane AG,Auber AE. MR imaging of heat stroke: external capsule and thalamic T1 shortening and cerebellarinjury. AJNR Am J Neuroradiol, 2003,24(7): 1372-1375.
  [13]Fujioka Y,Yasui K,Hasegawa Y,et al. An acute heat stroke patient showing abnormal diffuse high intensity of the cerebellar cortex in diffusio n weighted image: a case report. Clin Neurol, 2009,49: 634-640.
  [14]G Delgado,T Tunon, J Gdllego,et al.Spinal cord lesions in heat stroke [J], J Neurol Neurosurg Psychiatry,1985,48(10):1065-1067.
  [15]贺茂林。腔隙性梗死。神经病学/贾建平等主编。7版。北京:人民卫生出版社,2013.
  [16]Bynum GD, Pandolf KB, Schuette WH,et al. Induced hyperthermia in sedated humans and the concept of critical thermal maximum[J]. Am J Physiol, 1978,235:R228-R236.
  [17]钱红,乔文俊,于晓军,等。中暑合并全身炎症反应死亡1例[J].CHIN J FORENSIC MED, 2010:125-126.
  [18]Sakaguchi Y,Stephens LC,Makino M,et al, Apoptosis in tumors and normal tissues induced by whole body hyperthermia in rats[J]. Cancer Res 1995,55:5459-64.
  [19]Reynolds LPR, Allen GV. A review of heat shock protein induction fol lowing cerebellar injury [J]. Cerebellum 2003, 2(3):171-177.
  [20]Mahadik SP, Evans D,Lai H.Oxidative stress and role of antioxidant and Omega-3 essential fatty acid supplementation in schizoPhrenia[J] .Prog Neuro Psycho Pharmacol Biol Psychiatry, 2001,25(3):463-493.
  [21]Yeo TP. Heat stroke: a comprehensive review[J]. AACN Clinlssues 2004,15:280-93.
  [22]GabayC,Kushner I. Acute-phase proteins and other systemic responses to inflammation[J] .N Engl J Med,1999,340(6):448-54.
  [23]Hammami MM,Bouchama A, Al-Sedairy S, et al.Concentrations of soluble tumornecrosis factor and interleukin-6 receptorsin heatstroke and heatstress[J].Crit Care Med,1997,25(8):1314-1319
  [24]Asakura H,Suga Y,Yoshida T,etal. Pathophysiology of disseminated intravascular coagulation(DIC) progresses at a different rate in tissue factor induced and lipopolysac-charide-induced DIG models in rats [J]. Blood Coagul Fibrinolysis, 2003,14: 221 -228.
  [25]Bouchama A, Parhar RS,El-Yazigi A,et a/.Endotoxemia and release of tumor necrosis factor and interleukin 1 a in acute heat-stroke.J Appl Physiol 1991,70: 2640-2644.
  [26]Kourtis N, Nikoletopoulou V,Tavemarakis N. Small heat-shock proteins protect from heat-stroke-associated neurodegeneration[J]. Nature,2012,490(7419):213-218.
  [27]MoseleyPL.Heat shock proteins and heat adaptation of the whole Organism [J] J Appl Physiol, 1997,83:1413-1417.
  [28]LinMT.Heatstroke-induced cerebral ischemia and neuronal damage Involvement of cytokines and monoamines[J].Ann-N-Y-Acad-Sci, 1997, 813:572.
  [29]LinMT,Kao TY,Jin YT,et al.Interleukin-1 recepter antagorist attenuates the heat stroke-induced neuronal damage by reducing the cerebral ischemia in rats[J].Brain Res Bull, 1995,37[6]: 595-598.
  [30]Segovia G,Del Arco A,Mora F.Endogenous glutamate increases extracellular concentrations of dopamine, GAB A, and taurine through NMDA and AMPA/kainate receptors in striatum of the freely moving rat: a microdialysis study [J] J Neurochem, 1997, 69(4):1476-1483.
  [31]Yang YL,Lin MT.Heat shock protein expression protects against cerebral ischemia and monoamine overload in rat heatstroke[J].Am J Physiol,1999,276(6):H1961-1967.
  [32]Bindoli A,Rigobello MP,Deeble DJ.Biochemical and toxicological properties of the oxidation products of catecholamines[J].Free Rad Biol Med,1992,13: 391-405.
  [33]Ren Y,Li X,Xu ZC. Asymmetrical protection of neostriatal neurons against transient forebrain ischemia by unilateral dopamine depletion[J].ExpNeurol, 1997,146(1): 250-257.
  [34]Holmin S,Mathiesen T. Intracerebral administration of interleukin-ip and induction of inflammation, apoptosis,and vasogenic edema[J]. J Neurosurg 2000,92(1): 108-120.
  [35]Raj VMS,Alladin A,Pfeiffer B,et al. Therapeutic plasma exchange in the treatment of exertionalheat stroke and multiorgan failure[J]. Pediatr Nephroid 2013,28:971-974.
  [36]Wakino S,Hori S,Mimura T, et al.Heat Stroke With Multiple Organ Failure Treated With Cold Hemodialysis and Cold Continuous Hemodiafiltration: A Case Report [J]. Ther Apher Dial, 2005,9(5):423-428.
  [37] Yang TH,Shih MF,WenYS,et al .Attenuation of circulatory shock and cerebralischemia injury in heat stroke by combination treatment with dexamethasone and hydroxyethyl starch[J]. Experimental & Translational Stroke Medicine , 2010,2(19): doi:10.1186/2040-7378-2-19.
  [38]Niu KC,Chang CK,Lin MT,et al.A Hyperbaric Oxygen Therapy Approach to Heat Stroke with Multiple Organ Dysfunction[J]. Chinese Journal of Physiology,2009, 52(3):169-172.
  [39]Borovikova LV,Ivanova S,Zhang M. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin[J].Nature, 2000, 405(6785); 458-62.
  [40]Yamakawa K, Matsumoto N, Imamura Y,et al.Electrical vagus nerve stimulation attenuates systemic inflammation and improves survival in a rat heatstroke model [J]. PloS one, 2012,8(2): doi: 10.1371/joumal. pone. 0056728.g00L
  [41]职业性中暑诊断标准。职业卫生与应急救援。2009,27(4):174
  [42]第七届全国血栓与止血学术会议制定的几项诊断参考标准。中华血液学杂志。2000,21 (3): 165-168.
  [43]赵鹏飞,付小萌,王超,王红。多器官功能障碍综合征诊断标准及评分系统现状[J].临床和实验医学杂志,2013, 12(8) :630-636.
  [44]Bouges F,Vijayan G,JauVerally F. Peripheral neuropathy after heatstroke.Lancet 1987;i:224.
  [45]Pfeiffer QSteffen W. Guillain-Barre syndrome after heat stroke. J NeurolNeurosurg Psychiatry. 1999,66(3): 408.
  [46]秦宏,徐茜。职业性重症中暑合并格林-巴利综合征1例报道[J].环境与职业医学,2007 24(3) :325-326.

相关标签:
  • 报警平台
  • 网络监察
  • 备案信息
  • 举报中心
  • 传播文明
  • 诚信网站